Open surgery (open repair) is an option for severe cases of VUR

Surgery can be used for high-grade unilateral or bilateral VUR

The open surgical repair of vesicoureteral reflux (VUR) is most commonly used in grades IV and V VUR.¹ Endoscopic injection has assumed the role of first-line VUR treatment whereas reimplantation remains reserved for cases of failed injection therapy or significant anatomical abnormalities.²

What do children experience with open surgery?

• Prolonged hospital stay³
• Post-operative pain or discomfort³
• Possible complications such as bleeding, blockages of the ureters, bladder issues¹

Deflux has comparable protection to open repair

• A single head-to-head study reviewing charts of children treated with either Deflux or surgery to compare the incidence of febrile and febrile UTI occurrence postoperatively showed:⁴
  • Deflux postoperative rate of UTI recurrence: 5% (N=40)
  • Open repair postoperative rate of UTI recurrence: 24% (N=29)

Considerations of Deflux versus open surgery

• Comparable success rates with significant advantages: outpatient surgery, lower morbidity, fewer complications and reduced cost⁵
• Deflux is the preferred and most often used treatment among providers in academic settings for long-term cure of reflux.⁶
• VUR correction with Deflux is generally a 15-minute outpatient procedure requiring short-acting general anesthesia versus a lengthier inpatient procedure requiring general anesthesia²
• The procedure is considered minimally invasive with minimal post-operative pain and no need for urinary catheter⁷
• Children can usually return to school or normal activities the day after the procedure versus a surgical reimplant that generally requires hospitalization for post-operative pain and temporary urinary catheter drainage.⁷