VUR in Children

Symptoms &
Causes

About Deflux®

Is It The Right Choice
For Your Child?

My Child Has VUR

Quick Facts
& Resources

Katie’s Story

One Family’s Journey
Through VUR Treatment

What is VUR

Urine is made in the kidneys. Normally, urine only flows in one direction – from the kidneys down the ureters and into the bladder. VUR is a condition where urine flows backward from the bladder into the ureters and sometimes back up to the kidneys.

Since urine from the bladder is no longer sterile, VUR can increase the risk of urinary tract infections and may cause long-term kidney damage if left untreated.

The Deflux Advantage

Deflux is an injectable gel used to treat VUR. It is injected at the spot where the ureter connects to the bladder. This will help keep urine from flowing back into the ureters and kidneys. Eventually, new tissue grows around the gel providing long-term results.

The procedure usually takes about

15 minutes

and allows children to go back to normal activities the next day.1

Safe Treatment for VUR

Deflux has been used safely for over two decades to treat children with VUR.2

More than

400,000

procedures performed to date3

Deflux - Effective Treatment for VUR

Deflux works well to treat VUR with the majority of children having success after one injection.4

In long-term studies, after one injection of Deflux:

93%

had no fUTIs within 19 months4

REFERENCES:
  1. Cerwinka WH, Scherz HC, Kirsch AJ. Endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid in children. Advances in Urology. 2008; 1-7.
  2. Restylane® celebrates 25 years of natural-looking results with its signature line of hyaluronic acid fillers. 2021. Accessed: June 21, 2023. https://www.prnewswire.com/news-releases/restylane-celebrates-25- years-of-natural-looking-results-with-its-signature-line-of-hyaluronic-acid-fillers-301388779.html.
  3. Data on file. Palette Life Sciences.
  4. Kalisvaart JF, Scherz HC, Cuda S, Kaye JD, Kirsch AJ. Intermediate to long-term follow-up indicates low risk of recurrence after double hit endoscopic treatment for primary vesicoureteral reflux. J Pediatr Urol. 2012;8(4):359-36.
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